Protein Info for GFF1756 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: DNA recombination and repair protein RecF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 PF13175: AAA_15" amino acids 1 to 48 (48 residues), 41.6 bits, see alignment 3.3e-14 PF13514: AAA_27" amino acids 1 to 93 (93 residues), 27.8 bits, see alignment E=4.7e-10 TIGR00611: DNA replication and repair protein RecF" amino acids 1 to 355 (355 residues), 462.8 bits, see alignment E=4.4e-143 PF02463: SMC_N" amino acids 3 to 355 (353 residues), 163.9 bits, see alignment E=9.8e-52 PF13476: AAA_23" amino acids 5 to 92 (88 residues), 39.9 bits, see alignment E=1.9e-13

Best Hits

Swiss-Prot: 100% identical to RECF_SALNS: DNA replication and repair protein RecF (recF) from Salmonella newport (strain SL254)

KEGG orthology group: K03629, DNA replication and repair protein RecF (inferred from 99% identity to sew:SeSA_A4048)

MetaCyc: 95% identical to recombination mediator protein RecF (Escherichia coli K-12 substr. MG1655)
RXN0-2606

Predicted SEED Role

"DNA recombination and repair protein RecF" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (357 amino acids)

>GFF1756 DNA recombination and repair protein RecF (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSLTRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQPGRV
IRHEQEAFVLHGRLQSEERETSIGLTKDKQGDSKVRIDGTDGHKIAELAHLMPMQLITPE
GFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQRNAALRQVSRYEQLRPWDKE
LIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTFSFQRGWEKETDYADVLERSFER
DRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYL
IDDFASELDDARRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD