Protein Info for GFF1743 in Xanthobacter sp. DMC5

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 PF00072: Response_reg" amino acids 25 to 128 (104 residues), 79.6 bits, see alignment E=5.1e-26 PF07568: HisKA_2" amino acids 177 to 249 (73 residues), 83.7 bits, see alignment E=2e-27 PF07536: HWE_HK" amino acids 177 to 246 (70 residues), 25.6 bits, see alignment E=4.3e-09 PF13581: HATPase_c_2" amino acids 270 to 364 (95 residues), 39.7 bits, see alignment E=1.2e-13 PF02518: HATPase_c" amino acids 277 to 368 (92 residues), 47.2 bits, see alignment E=7e-16

Best Hits

KEGG orthology group: None (inferred from 83% identity to xau:Xaut_2333)

Predicted SEED Role

"putative signal transduction histidine kinase with response regulator receiver domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>GFF1743 Sensor histidine kinase RcsC (Xanthobacter sp. DMC5)
MECAVSDPLAVQPDAASAPPPPLRVLYVDDDPALGRLVQRQLGRLGFEVVPAFSGEDGLA
RLGTERFDVVALDHYMPGQDGMATLRAIRALENAPPVVYVTGAQDGRLAVAALKAGAADY
VVKEVQADFIELLRAAFVLAVEQVRMRRAHEAAEAEIRAARDRFEALAAERALLLREMNH
RVGNSLQIIVSLLNVQAGATEDPRVKEALNSARNRVSAVAQVHRRLYTSDQIATVALDQY
IGSLLDDLQVSAHREHGGITLTYDADPIHIDPDRGVALGIIATELVINAMKYAYPDGEGP
VRVKLKRMGDRLDFTVEDDGAGISPEKPATSTGLGNRIVKAMSMKLGCEPTFDPRERGTC
VRLTFRLADRGKA