Protein Info for PS417_08765 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 37 to 55 (19 residues), see Phobius details amino acids 67 to 84 (18 residues), see Phobius details amino acids 90 to 112 (23 residues), see Phobius details amino acids 124 to 142 (19 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 206 to 223 (18 residues), see Phobius details amino acids 238 to 255 (18 residues), see Phobius details amino acids 267 to 284 (18 residues), see Phobius details amino acids 290 to 310 (21 residues), see Phobius details amino acids 328 to 348 (21 residues), see Phobius details amino acids 354 to 373 (20 residues), see Phobius details PF07690: MFS_1" amino acids 7 to 213 (207 residues), 95.4 bits, see alignment E=3.4e-31 amino acids 207 to 375 (169 residues), 56.3 bits, see alignment E=2.6e-19 PF00083: Sugar_tr" amino acids 36 to 175 (140 residues), 35.8 bits, see alignment E=4.6e-13

Best Hits

Swiss-Prot: 47% identical to YDER_BACSU: Uncharacterized MFS-type transporter YdeR (ydeR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU1794)

Predicted SEED Role

"Major facilitator family transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U9E3 at UniProt or InterPro

Protein Sequence (384 amino acids)

>PS417_08765 MFS transporter (Pseudomonas simiae WCS417)
MVMLFAFCCGAIVANIYYAQPIIELIAPDIGLTPAMASLIVSLTQIGYALGLFFLVPLGD
LLENRKLMIATTVLAIASLLGAAFTEQPNLFLLVSLLIGFSSVSVQILIPLAAHLAPAES
RGRVVGSIMGGLLLGILLARPVSSVVADHFGWRAMFMAAAALMALISVVLLITIPKRQPD
HSATYGQLLRSLGTLLREQPVLRQRAFYQGCMFATFSLFWTAAPLELARNHGLSQSEIAL
FALVGALGAIAAPVAGRLADAGHTHRASLLAMLFAALSFLPAFVHPLYSVIGLAVTGVVL
DFCVQMNMVLGQRAIYALDANSRSRLNALYMTSIFIGGAFGSAIASSVYEHGGWLGVMLV
GSAFPLIALLRFLSASRQATVATA