Protein Info for GFF1705 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate) / C-terminal AAA-associated domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 PF00005: ABC_tran" amino acids 35 to 174 (140 residues), 111.7 bits, see alignment E=4.3e-36 PF09821: AAA_assoc_C" amino acids 314 to 429 (116 residues), 90.7 bits, see alignment E=1.1e-29

Best Hits

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 81% identity to hse:Hsero_0539)

Predicted SEED Role

"ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component" in subsystem Alkanesulfonate assimilation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (453 amino acids)

>GFF1705 ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate) / C-terminal AAA-associated domain (Variovorax sp. SCN45)
MNTTSRSPEPAKPVAELCAVTKTFRTAGNHELKVLDNIDLAVNEGEFLALLGQSGSGKST
ILRCLTGLIEPTSGRALANGKSLNGVNPDASIVFQTFALYPWLTVEQNVAVGLMSRKISR
AERDAAVDRAIELIGLGNYHAAFPRELSGGMRQRVGIARALVSRPRLLCLDEAFSALDVL
TAENLRQELISLWRGPNGDLSSVFMVTHNIEEAVEMATRIVVVFPRPGRVGLVLENKLPY
PRDTKDPEFQRLVSVIHESITTMTLPDLPPEAPEKGQPISRARTRMESIPLVPVGQILGL
MSILSDSPDLSNIYDISDEIGKEFGETIAILKAAEILDLIDTPRQEVRFTELGRKFVAAD
RLGKRAIFEEQVFKLRLFHIIIALLKEYEEVEAERVIKDIGSALPYDNPEKTFETMIAWG
RYAGLMDYNAKTGMVFVPQSDDSSDDAHLHGMT