Protein Info for GFF1704 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Periplasmic molybdate-binding domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 PF00126: HTH_1" amino acids 26 to 83 (58 residues), 39.2 bits, see alignment E=1.1e-13 PF12727: PBP_like" amino acids 139 to 325 (187 residues), 208.1 bits, see alignment E=1.4e-65 PF13531: SBP_bac_11" amino acids 195 to 327 (133 residues), 29.2 bits, see alignment E=1.6e-10

Best Hits

KEGG orthology group: None (inferred from 64% identity to mpt:Mpe_A0339)

Predicted SEED Role

"Periplasmic molybdate-binding domain" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>GFF1704 Periplasmic molybdate-binding domain (Hydrogenophaga sp. GW460-11-11-14-LB1)
MLRITLQPQWRVSQEDGPALDANTLLGLLAAVQGSGSISQAGRELGLSYRHAWGLLQQAE
QLFGQPLLVRGRGRGSVLTPLGEKLIWADARIGARLQPLLESLASELEGELGRVQRRQRA
VPRLHASHGFAVAALREQLAARQVPVELRYRSSLEAVAALAQGDCELAGFHVPLGEFEAA
AARRYLTWLKPDQHLLVQLAVRTQGLFVAAGNPLGLRGLGDLARPGLRFVNRPEGSGTRV
LTDLLLKREGIAPQAVAGYDNTELTHAAVAAYVASGMADVGIGVQTAAHRFGLHFIPLLK
ERYFFALPADALDRAELRPVLTVLRSPGFRARVAALKGYEAAHTGEVMGVAAAFQA