Protein Info for PS417_08665 in Pseudomonas simiae WCS417

Annotation: molybdopterin-guanine dinucleotide biosynthesis protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR02665: molybdenum cofactor guanylyltransferase" amino acids 10 to 193 (184 residues), 189.2 bits, see alignment E=3.7e-60 PF12804: NTP_transf_3" amino acids 13 to 168 (156 residues), 120.8 bits, see alignment E=3.2e-39

Best Hits

Swiss-Prot: 88% identical to MOBA_PSEFS: Molybdenum cofactor guanylyltransferase (mobA) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K03752, molybdopterin-guanine dinucleotide biosynthesis protein A (inferred from 88% identity to pfs:PFLU1753)

Predicted SEED Role

"Molybdopterin-guanine dinucleotide biosynthesis protein MobA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U9C6 at UniProt or InterPro

Protein Sequence (200 amino acids)

>PS417_08665 molybdopterin-guanine dinucleotide biosynthesis protein A (Pseudomonas simiae WCS417)
MPIDSSLLPCSVLLLSGGRGQRMGGQDKGLLEWRGQPLIAHVQHLVRPLTDDLIISCNRN
PQHYAAYADQLVNDDSPDFPGPLAGIRAGLAAARHAHLLILPCDVPHIDAGLIQALRETA
QRNPRLPVMVRHGAFWEPLICIVPTGLRDAVDSAWHAGERSPRKLFLQLGGVGLECPADD
PRLANLNTPELLQTPSGVSE