Protein Info for GFF1701 in Xanthobacter sp. DMC5

Annotation: Acetylornithine deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01892: acetylornithine deacetylase (ArgE)
  • amino acids 7 to 376 (370 residues), 361.8 bits, E=2e-112
• PF01546: Peptidase_M20
  • amino acids 67 to 378 (312 residues), 111 bits, E=7.8e-36
• PF07687: M20_dimer
  • amino acids 171 to 277 (107 residues), 78.5 bits, E=3.6e-26

Best Hits

KEGG orthology group: K01438, acetylornithine deacetylase [EC: 3.5.1.16] (inferred from 82% identity to xau:Xaut_2582)

Predicted SEED Role

"Acetylornithine deacetylase (EC 3.5.1.16)" in subsystem Arginine Biosynthesis extended (EC 3.5.1.16)

MetaCyc Pathways

• L-arginine biosynthesis I (via L-ornithine) (9/9 steps found)
• superpathway of arginine and polyamine biosynthesis (14/17 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (8/9 steps found)
• L-ornithine biosynthesis I (5/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.16

Use Curated BLAST to search for 3.5.1.16

Protein Sequence (390 amino acids)

>GFF1701 Acetylornithine deacetylase (Xanthobacter sp. DMC5)
MQVSTEEILEKIISVPSVTDTENGEIVARIAEIAAPFARVRHLPNAAGDRAALLLSIGPE
ERPGVVLSAHTDVVAVEGQPWTSDPFALTARGDRLYGRGTSDMKGFVACVLAALPAFAAA
ALETPVHVALSYDEEIGCKGAGDLVALLAALPMPPLLCIVGEPTGMKVKRAHKGKTGWRV
TATGRTGHSALPHRAANAVTALARLAARLADLADDLRGGARDEAFDPPYATLHIGSLHGG
GALNVVPDRAVMEFELRSIPGADTPTILRRIEVLVAEARAALKAEAEEADLVVEELSSYP
ALATAAGSAEAAAVARLCGDNGPPGTIAFGTEAGLYSEAGIPTLVCGPGDIARAHKADEW
VGRDELAQCDAMLARLAELLRRPAADWITP