Protein Info for GFF1652 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 52 to 74 (23 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 107 to 127 (21 residues), see Phobius details amino acids 146 to 192 (47 residues), see Phobius details amino acids 224 to 241 (18 residues), see Phobius details amino acids 254 to 277 (24 residues), see Phobius details amino acids 289 to 308 (20 residues), see Phobius details amino acids 313 to 336 (24 residues), see Phobius details amino acids 349 to 370 (22 residues), see Phobius details amino acids 376 to 398 (23 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 224 (195 residues), 76.3 bits, see alignment E=1.1e-25 amino acids 231 to 403 (173 residues), 57.1 bits, see alignment E=7.5e-20

Best Hits

KEGG orthology group: None (inferred from 92% identity to vpe:Varpa_4099)

Predicted SEED Role

"putative major facilitator superfamily (MFS) transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (413 amino acids)

>GFF1652 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MSSPPAASTSSPESPFSLWRIAVPAFAPSLLFGLGEGAILPIVPLTARDLGASVPMAALV
IAMIGIGSLINNIPASMITMRWGERWAIVAAGVWSGLGMLLCVLTSHLGLFATGCFMVGM
SQAVYNLARQSYMTEAVPVAYRARALSTLGGVMRIGMFAGPFLAAAAVHAFGLSAAYVVG
IVAVLGAAAIGARIPDLETPPVPAGQTAPASTSVVSTLRDHRRVFLTLGVGVVLVSAVRA
SRQAVIPLWADHLMLAPSVASLIYGLAGGIDMLVFYPAGKVMDRKGRRWVAVPSMLIMGL
AMLLIPLTSGALTLLLASLAIGFGNGIGSGMIMTLGADQSPRHGRAHFLGIWRLMSDIGS
SCGPALLSLLAGGLSLAAGIAVTGLIAFAAAGTLAYWIPRRGSAGGAGSTAPR