Protein Info for GFF1629 in Variovorax sp. SCN45

Annotation: Ferric reductase (1.6.99.14)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 TIGR03951: siderophore-iron reductase FhuF" amino acids 60 to 241 (182 residues), 122.7 bits, see alignment E=9.1e-40 PF06276: FhuF" amino acids 66 to 204 (139 residues), 56.8 bits, see alignment E=4e-19 PF11575: FhuF_C" amino acids 224 to 241 (18 residues), 26.2 bits, see alignment (E = 5.6e-10)

Best Hits

KEGG orthology group: K13255, ferric iron reductase protein FhuF (inferred from 54% identity to vpe:Varpa_4321)

Predicted SEED Role

"Ferric reductase (1.6.99.14)" in subsystem Anaerobic respiratory reductases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (250 amino acids)

>GFF1629 Ferric reductase (1.6.99.14) (Variovorax sp. SCN45)
MIPLLAPIFRGEWAAYGEALACAPQPPAGAVRVADLVTDPALLAGLLQAHARHLRMRKPD
LRPVASAWSMDYLSALLPPVAAAASLLQHVFPMAPAQVWLTLADGAVPQRFHIPHEGQAL
AGADTAARYAVLLHEHLAPLFAQLTRLTRIAPKILWGNASRYLEPVLEQGLALSGHAPSI
ARDLQHLLHQPHWGGDDNPMFTVQRKVVRMHAGAPEPLTLHRQCCLYYLLPEEGYCGACP
LAPQFRKTTG