Protein Info for GFF1613 in Variovorax sp. SCN45

Annotation: Phosphonate ABC transporter permease protein PhnE (TC 3.A.1.9.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 84 to 104 (21 residues), see Phobius details amino acids 130 to 153 (24 residues), see Phobius details amino acids 186 to 207 (22 residues), see Phobius details amino acids 216 to 235 (20 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details TIGR01097: phosphonate ABC transporter, permease protein PhnE" amino acids 26 to 268 (243 residues), 301.9 bits, see alignment E=1.8e-94 PF00528: BPD_transp_1" amino acids 96 to 269 (174 residues), 81.1 bits, see alignment E=4.4e-27

Best Hits

Swiss-Prot: 45% identical to PTXC_PSEST: Phosphite transport system permease protein PtxC (ptxC) from Pseudomonas stutzeri

KEGG orthology group: K02042, phosphonate transport system permease protein (inferred from 74% identity to ppg:PputGB1_3257)

Predicted SEED Role

"Phosphonate ABC transporter permease protein phnE (TC 3.A.1.9.1)" in subsystem ABC transporter alkylphosphonate (TC 3.A.1.9.1) (TC 3.A.1.9.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>GFF1613 Phosphonate ABC transporter permease protein PhnE (TC 3.A.1.9.1) (Variovorax sp. SCN45)
MKHPSTPYTWTGPRPEGRRGWFNLLVGACILGWALQWSADGAQLSWSELAAGLPQIVDFL
SRTLPPDMHILSRLVAPALETVQIAVWGTLLGVLPAIPLSFLAARNLQSNRWVYQGTRQA
LNVVRSINELILALVFVSAVGLGPFPGVLALALHGAGMLGKFFADAIEEIDQGPLEALRA
TGARPLQVIVFGVLPQVLTAWIAVVLYRFEVNLRSATVLGMVGAGGLGFELVSSLKLFRY
PETATCIIIITVMVIVADTLSSQLRHRIQRSGRH