Protein Info for GFF1594 in Variovorax sp. SCN45

Annotation: Antitoxin DinJ (binds YafQ toxin)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 102 TIGR02384: addiction module antitoxin, RelB/DinJ family" amino acids 1 to 55 (55 residues), 57.9 bits, see alignment E=4.7e-20 PF04221: RelB" amino acids 4 to 53 (50 residues), 52 bits, see alignment E=5.5e-18 PF21217: PaaA2" amino acids 56 to 82 (27 residues), 51.5 bits, see alignment E=8.2e-18

Best Hits

KEGG orthology group: K07473, DNA-damage-inducible protein J (inferred from 73% identity to cak:Caul_3631)

Predicted SEED Role

"DNA-damage-inducible protein J" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (102 amino acids)

>GFF1594 Antitoxin DinJ (binds YafQ toxin) (Variovorax sp. SCN45)
MAANALVQTRIDAEIKERATAVLDNIGLSVSDVMRIVLTRVAKEGALPAGLTVDPAAYDA
WFRAKVQEALDDPRPGIPHEKVEAHFAKRRAAAQLKAGEGGA