Protein Info for GFF159 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 PF00072: Response_reg" amino acids 9 to 118 (110 residues), 106 bits, see alignment E=3.2e-34 PF00158: Sigma54_activat" amino acids 146 to 304 (159 residues), 123 bits, see alignment E=2.6e-39 PF14532: Sigma54_activ_2" amino acids 147 to 309 (163 residues), 61.9 bits, see alignment E=2e-20 PF07728: AAA_5" amino acids 169 to 298 (130 residues), 23.9 bits, see alignment E=9e-09 PF02954: HTH_8" amino acids 387 to 425 (39 residues), 35.6 bits, see alignment 1.6e-12

Best Hits

KEGG orthology group: K10126, two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD (inferred from 48% identity to sal:Sala_1458)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>GFF159 hypothetical protein (Sphingobium sp. HT1-2)
MTDMPPRPIALVDDDDDLRAAMAQTLTLAGHEVRAFARAADALAAIDADFPGVVVSDVRM
PHMSGIDLFRALHARDAELPVILVTGHGDVPMAVDALKAGAWDFLTKPFNPDALLASVAR
ASEKRLLVIENRRLRAMVDTAVASPLIGHSPAIERLRDMVATLADTNIDILVEGETGTGK
ELVARMIHQRSRRASAQFVSIACAAVPDAIAETSLHGESLAGRAPLEGRLARAHQGTLFL
DDVDQSGPALQAHLIQFLEDRLVRPVGAREPQPVDLRVIGCMTQQGQAATIQPALLYRLA
AVRLHIPPLRERREDIPLIFAHLLDAAARRFRRTVPPVSRAVLAHLLDHDWPGNVHELGR
LAERLALGLEQEPVADGATLPLDARMDAFERMAIIEAIQATGGDMGQAIERLGLPRKTFY
YRVRRLGIDLRKLRGLDG