Protein Info for GFF158 in Sphingobium sp. HT1-2

Annotation: Zinc-regulated outer membrane receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 703 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07715: Plug" amino acids 52 to 156 (105 residues), 69.4 bits, see alignment E=5.2e-23 PF00593: TonB_dep_Rec_b-barrel" amino acids 265 to 672 (408 residues), 136.8 bits, see alignment E=3e-43 PF14905: OMP_b-brl_3" amino acids 415 to 579 (165 residues), 34.8 bits, see alignment E=1.5e-12

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 69% identity to sjp:SJA_C1-18900)

Predicted SEED Role

"Zinc-regulated outer membrane receptor" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (703 amino acids)

>GFF158 Zinc-regulated outer membrane receptor (Sphingobium sp. HT1-2)
MQFQFLAGCALAVLGISTAAHAQTASDDAADGYHQATRSDIIVTGILPTRRQDMLSSVAV
VEGKDLTQAIRPSIGETLERQPGVSATSFGPSASRPVLRGLQGERVKMLNNSLSTVDVSN
TSVDHAVVVNPLLAERIEVLRGPQSLLYGSSAIGGVVNVIDKRIPNAIPDEPVHVDAIGT
YGSAADERSGAASVDVPLSGGWVAHADGSYLKSDDVRIGGHALTPALRAEALASSLLPAD
DSEEAIDFAGNAAVKGKLPNSAAKTWTAGGGIAYIGDTGNIGISYDHYDSLYGVPIRFAT
QPGDEQEAPRLSMKQDSVNLRAEVNGDGNVLDKVSLRLGYADYTHAELEEDGSVGPAFFS
KGMEARLELTQAKHGAWRGATGVQLFNRDFNVIGEEAFLPKNSTTQVGVFTLQQLDYGAL
KFELGGRYEHTSLTANPLEDQEQFFAGKRSFDAFSGSVGASYGLTDSWRIGLNLSHTERA
PAAEELFANGPHAGTQAYEVGNPDFNLEKANSVEAILRGSGDNYSFEASAYHTWFSNFIY
EDLTGEEEDGLPVYAFNQADARYYGFEVQGSLTLAKLGDGKIVADGLADYVHANVKSVGP
APRIPPLRLLGGLAYQATKFDLRGEVERVSKQDRVAEFETTTPGYTMVNAELNVRPWGKE
RPLSFALSANNIFDVVARRASSFLKDYAPLTGRDIRVTARVSF