Protein Info for GFF1577 in Sphingobium sp. HT1-2

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 transmembrane" amino acids 20 to 45 (26 residues), see Phobius details amino acids 52 to 75 (24 residues), see Phobius details amino acids 86 to 108 (23 residues), see Phobius details amino acids 113 to 133 (21 residues), see Phobius details amino acids 144 to 160 (17 residues), see Phobius details amino acids 167 to 196 (30 residues), see Phobius details amino acids 232 to 253 (22 residues), see Phobius details amino acids 260 to 282 (23 residues), see Phobius details amino acids 294 to 340 (47 residues), see Phobius details amino acids 349 to 372 (24 residues), see Phobius details amino acids 384 to 402 (19 residues), see Phobius details PF05977: MFS_3" amino acids 13 to 530 (518 residues), 632.9 bits, see alignment E=4e-194 PF07690: MFS_1" amino acids 25 to 369 (345 residues), 110.5 bits, see alignment E=8.7e-36

Best Hits

KEGG orthology group: None (inferred from 79% identity to sjp:SJA_C1-20770)

Predicted SEED Role

"MFS permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (556 amino acids)

>GFF1577 Uncharacterized MFS-type transporter (Sphingobium sp. HT1-2)
MVFVPDTESPQPSSPFAIPIFRAIWIASLASNFGGLIQSVGAAWMMTSLSASPVLVALVP
ASTTLPIMLFSLWAGAVADNLDRRKVMMACQLFMLLVSTALALVAWLGALTPWTLLGFTF
LIGCATAVNGPAWQASVGDMVPRSVLPSAVAMNSMGFNLARSTGPALGGVIVAAAGAAAA
FLANAVSYIGLVAVLARWRPELPPKLLPRERLGVAMWAGVSYVSMSPKIQLVLLRGGAFG
IGASAVSALMPLVARDVLGGGALTFGLTSGAFGVGAVAGALSTRRLRARFSIEAIVRSAA
LSLAAGTAITAMSGYLALALLGYLLAGAGWVMALSTFNVSVQMSAPRWVVARAVAIYQMT
AFGGMAIGAWLFGNLAEDHGVVEALYASAAVQLVAALIGFVRPLPQIGDDNLDLQNRWRE
PETAVPVEPRSGPVVITIEYRIPVGSVVPFLSAMSERRRIRKRDGAHGWSLMRDLGDPEL
WVERYHVSTWLDYVRHNQRRTIADITNSDTIHALHSGGKPPVVHRMLERQTGSLPLSRAP
DPREMGDGLTDPTRST