Protein Info for GFF1567 in Xanthobacter sp. DMC5

Annotation: Putative multidrug resistance protein MdtD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 transmembrane" amino acids 23 to 46 (24 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 115 to 138 (24 residues), see Phobius details amino acids 150 to 174 (25 residues), see Phobius details amino acids 180 to 198 (19 residues), see Phobius details amino acids 209 to 228 (20 residues), see Phobius details amino acids 244 to 268 (25 residues), see Phobius details amino acids 296 to 319 (24 residues), see Phobius details amino acids 327 to 348 (22 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details amino acids 384 to 410 (27 residues), see Phobius details amino acids 431 to 454 (24 residues), see Phobius details amino acids 511 to 530 (20 residues), see Phobius details PF07690: MFS_1" amino acids 29 to 202 (174 residues), 75.5 bits, see alignment E=1.9e-25 amino acids 233 to 437 (205 residues), 57.7 bits, see alignment E=5.2e-20

Best Hits

KEGG orthology group: None (inferred from 79% identity to ypa:YPA_1323)

Predicted SEED Role

"Putative MFS Superfamily multidrug efflux transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (551 amino acids)

>GFF1567 Putative multidrug resistance protein MdtD (Xanthobacter sp. DMC5)
MTGSTPAQSLAGQPPGQEAKESWVPMIAIALGQVIMSFNVASLPVAMGGMVKSFNVPPTT
IATGIVMYSMLVAGFVMLGAKLNQRFGAVNVFRATVVLFGCAQVLMTFSPNATVMITAQG
LSGAAAAAIVPSLVALIAENYRGTQQATALGALGSARAAAGVAAFLIGGVLGTFIGWRPA
FGILIVLSAVVFVLSFRLKADRGRPEVQIDLVGVVLAAAAIVLISFGFNNLNRWGLAVAT
PAAPFTIAGLSPAPVFIVAGIVLGQLFVRWTRRRQEAGKTPLLALEVITSGQERAAVMAM
FAVVALEAMLNFSVPLYIQIVQGRSPLATAIAMMPFNLTVFFSAMLIVRFYDKLTPRQIG
RYGFILCTVALVWLAFVVRNDWSAVPVLFGLVVFGIGQGSLVTLVFNVLVTASPKELAGD
VGSLRGTTNNLAAAVGTAVAGALLVGLLSTIVLGRVAATPELTPEVQAMVNLDSINFVSN
DRLRTALETAGATPQQVNAAVVVNAESRLRALKIGLLIMAAIALLSIIPAGRLPDYKPGE
IPDPDKAPPAK