Protein Info for GFF1561 in Xanthobacter sp. DMC5

Annotation: Acid-activated urea channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 172 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 30 to 50 (21 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 116 to 136 (21 residues), see Phobius details amino acids 147 to 169 (23 residues), see Phobius details PF02293: AmiS_UreI" amino acids 3 to 168 (166 residues), 186.4 bits, see alignment E=2.2e-59

Best Hits

Swiss-Prot: 52% identical to AMIS_PSEAE: Putative transporter protein AmiS (amiS) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 84% identity to sno:Snov_1174)

Predicted SEED Role

"Urea channel UreI" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (172 amino acids)

>GFF1561 Acid-activated urea channel (Xanthobacter sp. DMC5)
MLLGLGLLYVGAVLVLNGLWLLGKIEDREIIVVNVVSGFVTLAISAYWAFNPAADAASIK
GAALTLLFTATYFWVAYNRVTKVDGRGLGWFSLFVAITVAPVAIQSLRGAETSIGLWMGW
NWVGWGLLWFCYFLLLTMKQPILKFTGAFTVLIGILTGWVPGLSLLQGWLNP