Protein Info for GFF1533 in Xanthobacter sp. DMC5

Annotation: HTH-type transcriptional regulator GntR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 PF00356: LacI" amino acids 13 to 58 (46 residues), 58.9 bits, see alignment 6.8e-20 PF00532: Peripla_BP_1" amino acids 72 to 317 (246 residues), 85.7 bits, see alignment E=8.1e-28 PF13407: Peripla_BP_4" amino acids 72 to 317 (246 residues), 60.4 bits, see alignment E=4.2e-20 PF13377: Peripla_BP_3" amino acids 179 to 339 (161 residues), 115 bits, see alignment E=8e-37

Best Hits

KEGG orthology group: K06145, LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor (inferred from 38% identity to rlg:Rleg_6417)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>GFF1533 HTH-type transcriptional regulator GntR (Xanthobacter sp. DMC5)
MRQKRGGRAAGVTMEDVARVAGVSAMTVSRVLRKPTLVNADLKARVEAAIRETGYIYNLV
ASSLASQRSGIIALILPTVASSIFTDSVKGVSDVARTHAVQMIMAETNYSPAEEEKVIEA
LLRRRPDGFVIVGVSHTRATRALLEKSGVPVVETWDSTPTPIDSLVGLSNFDAMKAMTEA
LVAQGFRRIVFVGTATPDRRAQMRAKGYEAGIAEAGLGAPLILNAGDLTSMESGRIIAER
IAALRPRPDAVLCLNDVLAAGALLAFQRMGITVPADIAVAGFGGLDFSSHLNPSLSTVDI
PRYEMGQKAAEMLLGRIAGTAAQGGTCEMGYRIMLRESTGGSRPTEAKAS