Protein Info for GFF1533 in Sphingobium sp. HT1-2

Annotation: Ferrichrome-iron receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 783 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF07715: Plug" amino acids 65 to 164 (100 residues), 77.3 bits, see alignment E=1.2e-25 PF00593: TonB_dep_Rec_b-barrel" amino acids 254 to 751 (498 residues), 160.3 bits, see alignment E=1.5e-50

Best Hits

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (783 amino acids)

>GFF1533 Ferrichrome-iron receptor (Sphingobium sp. HT1-2)
MAKYGNTPSFLALSCVGAMAFASGAHAQDNGQGQALGGVTVTDTAIDDNSIKVDKPESPK
YVRPLLDTPQTITVIGNQTIQKQNLLTLRDVLSTVPGITFGAGEGGGGYGDSINLRGQSA
NTDISIDGVRDSAQYSRTDPFNLEQIEVTNGANSVYGGSGAIGGNINLVTKRPKADSETL
VQGGIGTSDYYRATIDSNVRVNDLIAVRLNAMYHENDVPARQVDRYERWGVAPSVKLGVD
GPTSATLMFVHQEDKNTPLYGVPYYKNAVYDGPLPGVPYSSYMGYPNLDKQDQTVDQATL
IFDHQFSDTVSLRNLSRWQHVQQDLVVNPPQGAYCLANGTSATGAACAAGQQPGYYYPSG
PRGGFRNSDNQSLYNQLDLTFNIPGGHTLVIGTSAMQEDYVLDNGNVERNPGGATPNPTL
TPIPIGVPTDYTGPVNAIQSGHQVGDTFNFAAYAFAAAKIVDQLELNGGIRWEHNRARFR
SDTIATPALGGAYTTGAQQNATDNLFSYRIGLVFKPVENASLYAAYANSLTPTSSTVRAG
CGTASIDQIDLGLEPCGVDPQKAENFEIGGKIDLFDNGLQLTAALFRNKRTNYSVASNNP
AIGNLNVNDGRNKVDGITLGATGNITSNWTIFANYTYLKSKVLQSISDYCLANPGKFYTP
TGATQPVTCAMSDPQAGNPLTNTPKHSGSLFTTYTLPFGLQLGYGLTYQGSWYLSNSSTA
TMYKADDYLVHRAMLSYTFAEKLTAQLNVQNFTNEKYYTSIRNNGWANPGEGRSWVLTLG
YKL