Protein Info for GFF153 in Sphingobium sp. HT1-2

Annotation: Efflux ABC transporter, permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 130 to 150 (21 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 210 to 233 (24 residues), see Phobius details amino acids 241 to 259 (19 residues), see Phobius details amino acids 451 to 472 (22 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 7 to 265 (259 residues), 80.7 bits, see alignment E=2.3e-26 PF12730: ABC2_membrane_4" amino acids 132 to 232 (101 residues), 27.5 bits, see alignment E=5.7e-10 PF12698: ABC2_membrane_3" amino acids 136 to 253 (118 residues), 42.4 bits, see alignment E=1e-14 PF12040: DUF3526" amino acids 273 to 438 (166 residues), 125.9 bits, see alignment E=4.2e-40

Best Hits

KEGG orthology group: None (inferred from 69% identity to sch:Sphch_0151)

Predicted SEED Role

"FIG00952399: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>GFF153 Efflux ABC transporter, permease protein (Sphingobium sp. HT1-2)
MSAITLIARDELRLMRRNRVAVIAFALLVLLTLAAALISWSHQSGIAETRARFQAQAAEA
FEAQPDRHPHRMVHFGNFIFRPLPPLAAFDPGVDAFTGNSIFLEGHRQNSANFGDVRQSS
LLVRFGQLTPAFVLQVIAPLLLIFLGYGAVARERERGTLRQMLVQGVSARTLVMGKLLAL
AVVAALVGLPALIAFLLIAGQPGALAGPMAVIALGYGAYLALWSIIVILVSALVRRGRDA
LLALLALWAVLVILLPRVAPDIAAQAHGLPTRLETDIAIQQDLHRLGDAHNPDDPFFNAF
KQKVLRRYGVDKVEDLPVNYNGLLAVEGEKLTSGLFDDYADRSFAIQQAQSRLTNGFGII
SPAISLRQLSMAAAGTDLAGHRRFLAQAEAYRYAMVQHLNQLQADAVSYADDKAKDAGAD
QRKRISADHWQAIPQFRFIAPTAGDLVTASLPGLGLLLAWLVLALLALLPVARHLQKARP