Protein Info for GFF1528 in Xanthobacter sp. DMC5

Annotation: putative sulfate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 571 transmembrane" amino acids 31 to 51 (21 residues), see Phobius details amino acids 57 to 73 (17 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 139 to 157 (19 residues), see Phobius details amino acids 184 to 202 (19 residues), see Phobius details amino acids 214 to 239 (26 residues), see Phobius details amino acids 258 to 278 (21 residues), see Phobius details amino acids 296 to 315 (20 residues), see Phobius details amino acids 330 to 349 (20 residues), see Phobius details amino acids 353 to 377 (25 residues), see Phobius details amino acids 389 to 419 (31 residues), see Phobius details amino acids 453 to 464 (12 residues), see Phobius details PF00916: Sulfate_transp" amino acids 28 to 393 (366 residues), 291.4 bits, see alignment E=1.4e-90 PF01740: STAS" amino acids 446 to 555 (110 residues), 57.6 bits, see alignment E=1.4e-19 PF13466: STAS_2" amino acids 477 to 539 (63 residues), 30.4 bits, see alignment E=5.5e-11

Best Hits

Swiss-Prot: 40% identical to Y1739_MYCTO: Probable sulfate transporter MT1781 (MT1781) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 64% identity to rhi:NGR_c18710)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (571 amino acids)

>GFF1528 putative sulfate transporter (Xanthobacter sp. DMC5)
VAADGASSQEAPRTLLASFAGYRPGWIKTDVAAGLAIAAVGLPSAIAYPAIAGLPPQTGL
YASIAPLIAYAVFGPSRQLVVGPDAATITVLAAVLAGMPDLAAVDKPGVAALIALVVGGY
YFAARLVGLGVLSTFLSRPILVGFFAGISLSILVGQLKRVTGIPIVGDGLIAPVIELVRK
AHEVHWPSLLLALSMFAVLHLVRRTRLPVPGQVVVVVLSVVLSALFDFAGHGIAVVGSIP
SSLPALALPAGGGAAIDQLLIGAAAIFLVSFAAGIVTARSFGERGGYPVDANREMVGFGA
ANIAAGLFAAFPITASDSRTAVNASVGGRSQLASVVAALALLAIVLFLQPALAILPIPAL
GAILISAALSLVDLPALRQLWRISRMEFAFAMIALFAPISLGVLNGVLIAIGATFAYLLH
KMMYPRDALLGRVPGHEGFYKLHRRADARQVPGLAIVLIQGDLLFFNADRMQGRIDAIAD
NLVDGTRWLVLDASAITQVDSTAAAALEEVRAELQRRGLKFGIAEMHDEVRTLLDHAGLL
GKIGSDMIFDDLDDAYRAFEASGEAPSPGGA