Protein Info for GFF1483 in Xanthobacter sp. DMC5

Annotation: Multidrug export protein AcrF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1021 transmembrane" amino acids 16 to 35 (20 residues), see Phobius details amino acids 337 to 356 (20 residues), see Phobius details amino acids 361 to 383 (23 residues), see Phobius details amino acids 389 to 413 (25 residues), see Phobius details amino acids 428 to 451 (24 residues), see Phobius details amino acids 463 to 491 (29 residues), see Phobius details amino acids 519 to 542 (24 residues), see Phobius details amino acids 855 to 874 (20 residues), see Phobius details amino acids 881 to 900 (20 residues), see Phobius details amino acids 906 to 930 (25 residues), see Phobius details amino acids 957 to 976 (20 residues), see Phobius details amino acids 982 to 1005 (24 residues), see Phobius details PF00873: ACR_tran" amino acids 7 to 1004 (998 residues), 521.8 bits, see alignment E=1.7e-160

Best Hits

KEGG orthology group: None (inferred from 83% identity to bra:BRADO1727)

Predicted SEED Role

"RND efflux transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1021 amino acids)

>GFF1483 Multidrug export protein AcrF (Xanthobacter sp. DMC5)
VKSFNLSDWALEHRSLVWYFMLAFVLAGFMSYLQLGREEDPAFTIKTMVIQAQWPGASAQ
EMTRQVTDRIEKKLEELEALDYTRSLTVPGQTTIFVNLRDTTKARDVVPTWLQVRNMVND
IRGTFPQGVTGPQFNDRFGDVYGNIYAFTSDGLTQRQLRDRVEEVRAQVLTVPNVGRVDI
IGAQDEVIFLEFSTRKMAALDIDQRAVLSSLQAQNALVPSGVLQAGPERIAVRVNGRFSS
EESLKAINLRINGRFFPLTDIATIRRGYVDPPQSLFRFNGEPAIGLAIGMKAGANLLQFG
EALKAEMTRIEADLPVGVGVHLVSDQPQIVEEAVGGFTRALMEAVIIVLAISFVSLGLRA
GLVVAISIPLVLAITFMVMAYTGISLQRISLGALIIALGLLVDDAMIAVEMMVARLEAGD
TLRKAATYVYTSTAFPMLSGTLVTVAGFIPIGLNNSNAGEFTFTLFVVIAVSLLVSWLVA
VLFTPLLGVAILPKSLPHHKEGGGRFARAFAWILKRAMLWRWTTIGVTVLVFILSLAGMG
LVQQQFFPSSDRRELIVDWNLPQNASIAETNAQMARFEQEVLKGNPDIDHWSTYVGTGAP
RFVLPVDVQPADVAFGQTIIVTKGLEERNRLKGQFQAYLDKAMPGTDAFVHFLDIGPPVG
RPVQYRVSGPDIQQVRTYALDFASVMRGNPHLGNVVFDWMEPARVIKVDVLQDKARQLGV
TSEDIAGALNGVLDGTAITQVRDDIYLVTVLGRANAQERQSIETLRDLQLPGSGGRSVPL
AAVATLRYEIEQPTIWRRSRLPTITAKAGIIDTAQPNTVVEQLTPAVAAFNAKLPPGYRV
VIGGAVEESQKSQAPILAVMPLMLFIMATILMIQLQSFQRLVLVFAVAPLALIGVVAALV
PSGAPLGFVAILGVLALIGILIRNSVILIVQIEQLRAEGRPPWDAVREATEHRMRPIMLT
AAAASLGLIPIAREVFWGPMAYAMMGGIIVGTVLTLLFLPALYVAWFRIPAPKPGDGAQA
G