Protein Info for GFF1463 in Xanthobacter sp. DMC5

Annotation: Sulfide dehydrogenase [flavocytochrome c] flavoprotein chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF07992: Pyr_redox_2" amino acids 34 to 135 (102 residues), 34.4 bits, see alignment E=3.3e-12 PF21706: FCSD_central" amino acids 164 to 280 (117 residues), 134.7 bits, see alignment E=3.3e-43 PF09242: FCSD-flav_bind" amino acids 355 to 422 (68 residues), 62.6 bits, see alignment E=7.5e-21

Best Hits

Swiss-Prot: 41% identical to DHSU_ALLVD: Sulfide dehydrogenase [flavocytochrome c] flavoprotein chain (fccB) from Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)

KEGG orthology group: None (inferred from 69% identity to xau:Xaut_1514)

MetaCyc: 41% identical to flavocytochrome c flavoprotein subunit (Allochromatium vinosum)
RXN-8156 [EC: 1.8.2.3]

Predicted SEED Role

"Sulfide dehydrogenase [flavocytochrome C] flavoprotein chain precursor (EC 1.8.2.-)" in subsystem Sulfur oxidation (EC 1.8.2.-)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.2.- or 1.8.2.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>GFF1463 Sulfide dehydrogenase [flavocytochrome c] flavoprotein chain (Xanthobacter sp. DMC5)
MARAGVSRRALLSGSALAAALLCAPHVAAQAKPRVVIVGGGAGGANAARALLRDGRVEVT
LVEPEPLYVAVFHSNLWLGGFIDFAALEFGYQGLARAGVRLVPQRADAIDRERREVRLAD
GGRLPYDRLILSPGIDLDYDSVPGWSRADETAMPHAWKGGAQLRLLKERLDLVPDGGLIV
IIAPPNPFRCPPAPYERASMMAHRLKTTGRGGARIIIVDPKPKFSMQGLFQEGWEGHYPG
MVEWMAPDISDGLVSVDPATGTVVTGFETYREAALVNVIPAQKAGAIARGAGLADASGWC
PVEAASMASALDPAVFVIGDAAIGGEIPKSAFAAGSQADVAVRALLAGLFGEAVPSASYA
STCWSLIAAEDAVKVSGLYRPVDGRIREVEGTVSGAGEPAALRRRQQQENADWYRAMVAG
MFG