Protein Info for GFF1462 in Sphingobium sp. HT1-2

Annotation: Deoxycytidine triphosphate deaminase (EC 3.5.4.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02274: deoxycytidine triphosphate deaminase
  • amino acids 3 to 183 (181 residues), 168.6 bits, E=5.8e-54
• PF22769: DCD
  • amino acids 3 to 157 (155 residues), 121 bits, E=2.4e-39

Best Hits

Swiss-Prot: 93% identical to DCD_SPHWW: dCTP deaminase (dcd) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 97% identity to sjp:SJA_C1-15760)

MetaCyc: 70% identical to dCTP deaminase (Rickettsia prowazekii Madrid E)
dCTP deaminase. [EC: 3.5.4.13]

Predicted SEED Role

"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)

KEGG Metabolic Maps

• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.13

Protein Sequence (184 amino acids)

>GFF1462 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) (Sphingobium sp. HT1-2)
MSILSDRWIRKQAQSNRMIEPFVENQRRDGCISYGLSSYGYDARVADEFKIFTNVDSAVV
DPKDFAANSFVDRKTDVCIIPPNSFALARTVEYFRVPRDVLVICLGKSTYARCGIIVNVT
PLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNEPCEVSYADRAGKYMGQQGVT
LPRL