Protein Info for GFF1458 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: Cytochrome c-type heme lyase subunit nrfG, nitrite reductase complex assembly
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 71% identical to NRFG_ECOLI: Formate-dependent nitrite reductase complex subunit NrfG (nrfG) from Escherichia coli (strain K12)
KEGG orthology group: K04018, formate-dependent nitrite reductase complex NrfG subunit (inferred from 97% identity to spt:SPA4100)Predicted SEED Role
"Cytochrome c-type heme lyase subunit nrfG, nitrite reductase complex assembly" in subsystem Nitrate and nitrite ammonification
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (206 amino acids)
>GFF1458 Cytochrome c-type heme lyase subunit nrfG, nitrite reductase complex assembly (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MSQSEHSTAPLRPMPVKRLAAAAVLMVAACVGGYLLTPKWQAVRSEQQRLADPLRDFTNP QTPEAQLSRLQEKIRANPQDSEQWARLGEYYLYRNAYDNALLAYRQALRLRGDNAQLFAA LATVLYYQAGQHMTPATREMINKALALDATEVTAQMLLAADAFMQADYAQAVSLWQTLLD ANSPRVNRAQLVEAINLAKLLQNRQK