Protein Info for GFF1444 in Sphingobium sp. HT1-2

Annotation: Selenoprotein O and cysteine-containing homologs

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 PF02696: SelO" amino acids 14 to 371 (358 residues), 393.7 bits, see alignment E=6.2e-122

Best Hits

KEGG orthology group: None (inferred from 79% identity to sch:Sphch_0281)

Predicted SEED Role

"Selenoprotein O and cysteine-containing homologs"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>GFF1444 Selenoprotein O and cysteine-containing homologs (Sphingobium sp. HT1-2)
MDNKPQAANYHPATEITALMPDIADPVHAADFPQTLLRFRNDRAAATVGLDHLSDAEWIA
HFGRFAPLPDNLPQPLALRYHGHQFRHYNPDIGDGRGFLFAQLRDADGRLLDLGTKGSGQ
TPYSRFGDGRLTLKGGVREILATEMLEALGVNTSKTFSIIETGEALERNDEPSPTRGAAM
VRLSHSHIRIGSFQRGAYIEDNGLLERLTDYALTRLYGEQPGDNPPAQLLGRVVDRTADL
AASYMVAGFVHGVLNSDNINVTGESFDYGPWRFTPLWDAGFTAAYFDHAGLYAFARQAEA
IHWDVAQLAVSLRPLTEAPPLIEQLERFPALYAQAMQRRFCWRLGIQPGTDSTAMTETAV
RAMMTTATPIDIFFHDWRGGTPRNPARYSEPIWAELRDQLTDHPPVPGARDHAYWSAEAP
CSMHIDEVEAIWSAIDQSDDWSPLHAKVTAIRRMGEAHGAAPALP