Protein Info for GFF144 in Xanthobacter sp. DMC5

Annotation: Signal recognition particle protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 TIGR00959: signal recognition particle protein" amino acids 2 to 428 (427 residues), 574 bits, see alignment E=9.4e-177 PF02881: SRP54_N" amino acids 5 to 82 (78 residues), 76.1 bits, see alignment E=3.1e-25 PF00448: SRP54" amino acids 102 to 296 (195 residues), 221 bits, see alignment E=1.8e-69 PF02978: SRP_SPB" amino acids 327 to 427 (101 residues), 108.3 bits, see alignment E=3.1e-35

Best Hits

Swiss-Prot: 52% identical to SRP54_ECOLI: Signal recognition particle protein (ffh) from Escherichia coli (strain K12)

KEGG orthology group: K03106, signal recognition particle subunit SRP54 (inferred from 96% identity to xau:Xaut_1464)

Predicted SEED Role

"Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)" in subsystem Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (514 amino acids)

>GFF144 Signal recognition particle protein (Xanthobacter sp. DMC5)
MFDTLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDRVRQRAV
GVEVIKSVTPGQMVVKIVHDELVATLGSDADPIDLNAPAPVPILMVGLQGSGKTTSTAKI
AKRLTERGKRKVLMASLDTRRPAAMEQLATLGKQVEVATLPIVAGQSAVQIAKRAIEAAK
LGGYDVVMLDTAGRVTLDEGLMAEVAEVKAVTGPHEVLLVADSLTGQDAVNTAKAFDGRV
GLTGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDALEDFDPHRVAGRILGMGDV
VALVERAAENIDIEKAKITAERMRKGTFDLDDLRGQLEQMAKMGGLGGLMGLMPGVAKVK
NQIASANLDDKVFKRQVAIINSMTPKERRAPKLLDASRKRRIAAGSGTKVEEINRLLKMH
RQMADVMKSLGGAAGKRGPLAGLAGMMGFGGGGPSPEMLQEMAEKMGKGGPGAPGGLPPN
FPGLPGGGLPSKFPGGLPGLPKGFPGVGGPSKKK