Protein Info for PS417_07265 in Pseudomonas simiae WCS417

Updated annotation (from data): 2-deoxy-D-ribonate transporter 1
Rationale: Specifically important for utilization of deoxyribose and deoxyribonate. Because deoxyribose is probably oxidized in the periplasm, this is probably a deoxyribonate transporter. It belongs to the MFS superfamily, and is in conserved proximity to other deoxyribonate utilization genes. Another putative transporter (PS417_07260) is also important for utilizing deoxyribose and deoxyribonate, which is not explained.
Original annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 112 to 135 (24 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details amino acids 179 to 198 (20 residues), see Phobius details amino acids 246 to 270 (25 residues), see Phobius details amino acids 279 to 301 (23 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details amino acids 337 to 357 (21 residues), see Phobius details amino acids 365 to 386 (22 residues), see Phobius details amino acids 400 to 419 (20 residues), see Phobius details PF07690: MFS_1" amino acids 25 to 386 (362 residues), 143.5 bits, see alignment E=3.9e-46

Best Hits

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU1496)

Predicted SEED Role

"Nitrate/nitrite transporter" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZ48 at UniProt or InterPro

Protein Sequence (438 amino acids)

>PS417_07265 2-deoxy-D-ribonate transporter 1 (Pseudomonas simiae WCS417)
MTTTPSARTPQALNKLMFVKLMPLLIIAYILSFLDRTNIALAKHHLDVDLGISAAAYGLG
AGLFFLTYALSEIPSNLIMHKVGARFWIARIMVTWGLISAAMAFVQGETSFYVLRLLLGI
AEAGLFPGVMLYLTYWFNREQRARATGYFLLGVCFANIIGGPVGAALMRMDGMLGWHGWQ
WMFMLEGLPAVAFAWVVWRKLPDRPSKAPWLSAEEARGIEQRIAQETEEGAGEGGHSLKN
WLTPQILLAIFVYFCHQITIYTVIFFLPSIISKYGELSTMSVGLLTSLPWIAAALGALLI
PRFATTPGRCRRLLVTGLLTMALGLGIASVSGPVFSLLGFCLSAVMFFVVQSIIFLYPAS
RLKGVALAGGLGFVNACGLLGGFVGPSVMGVIEQSTGNAMNGLKVIALVLVVAALAALRL
RMGHEPERGAQASEASYT