Protein Info for PS417_07135 in Pseudomonas simiae WCS417

Annotation: serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 479 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR02037: peptidase Do" amino acids 31 to 475 (445 residues), 522.9 bits, see alignment E=3.5e-161 PF00089: Trypsin" amino acids 99 to 255 (157 residues), 63.6 bits, see alignment E=6e-21 PF13365: Trypsin_2" amino acids 101 to 234 (134 residues), 134.1 bits, see alignment E=1.6e-42 PF00595: PDZ" amino acids 271 to 332 (62 residues), 40.1 bits, see alignment E=1e-13 amino acids 387 to 463 (77 residues), 31.4 bits, see alignment E=4.9e-11 PF13180: PDZ_2" amino acids 275 to 364 (90 residues), 61.1 bits, see alignment E=2.7e-20 amino acids 391 to 471 (81 residues), 35.2 bits, see alignment E=3.2e-12 PF17820: PDZ_6" amino acids 300 to 353 (54 residues), 38.5 bits, see alignment 2e-13 amino acids 414 to 466 (53 residues), 36.2 bits, see alignment 1e-12

Best Hits

Swiss-Prot: 90% identical to DEGPL_PSEF5: Probable periplasmic serine endoprotease DegP-like (mucD) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: None (inferred from 98% identity to pfs:PFLU1471)

Predicted SEED Role

"HtrA protease/chaperone protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UEG1 at UniProt or InterPro

Protein Sequence (479 amino acids)

>PS417_07135 serine peptidase (Pseudomonas simiae WCS417)
MSIPRLKSYLSIVATVLVLGQALPAQAVELPDFTQLVEQASPAVVNISTTQKLPERKVSN
QQMPDLEGLPPMLREFFERGMPQPRAPRGGGGGQREAQSLGSGFIISSDGYILTNNHVIA
DADEILVRLADRSELKAKLVGTDPRSDVALLKIEGKDLPVLKLGKSQDLKAGQWVVAIGS
PFGFDHTVTQGIVSAIGRSLPNENYVPFIQTDVPINPGNSGGPLFNLAGEVVGINSQIYT
RSGGFMGVSFAIPIDVAMDVSNQLKSGGKVSRGWLGVVIQEVNKDLAESFGLDKPAGALV
AQIQDDGPAAKGGLHVGDVILSMNGQPIVMSADLPHLVGALKAGSKAKLEVIREGKRQTV
ELTVGAIPEEGATLDALGNTKPGAERSSNRLGIAVAELTAEQKKTFDLKSGVVIKEVQDG
PASLIGLQPGDVITHLNNQAIDSTKQFTDIAKALPKNRSVSMRVLRQGRASFITFKLAE