Protein Info for GFF1392 in Sphingobium sp. HT1-2

Annotation: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 PF00501: AMP-binding" amino acids 12 to 356 (345 residues), 175.2 bits, see alignment E=1.9e-55 PF13193: AMP-binding_C" amino acids 417 to 492 (76 residues), 55 bits, see alignment E=1.3e-18

Best Hits

KEGG orthology group: None (inferred from 89% identity to sch:Sphch_0604)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (511 amino acids)

>GFF1392 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Sphingobium sp. HT1-2)
MSLTLQAVAPDRRTDMALTDERVSLDWLQLDDLLNRAANALNGLDLHERRVAVFAPNSAE
TVIAYVACLEAGISSVPVSFHLTPSEAAYILKDSGAVALLVGPETMEAGLAAAAEAGVAT
VIGWRCPDREGLIHWEAWLAAASTAEPDPSVAPLPHLHYTSGTTGRPKATETPPQYFPRV
ATVQALAETVRARITPSPGIAVGPLYHTGPLGMARNVFGGMSLITVEHFDAERALALIEK
YRVAGSVMVPTHFQRMLALPEEVRTKYDVSSIQRLAHTGAACPRAVKQAMIDWFGPVLVE
AYGGTEAGSTTFITSPEWLERPGSVGRALAPFETVIYGDDGAVLGANEVGQVYFRDTSGH
GIVYRGDPEKTAAAHIAPGIFTLGEMGYVDDAGYLFITDRVSDMIVSGGVNIYPAESEHV
LLRHPKVADIAVVAAPNAEMGEEARALVIPRDPADPPTADELNAFCRASLAGYKCPRGYE
MVDDIGRTIMGKVNKKALRQRFWPSDRTIGG