Protein Info for GFF1392 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: General secretion pathway protein F / Type II secretory pathway, component PulF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 transmembrane" amino acids 174 to 197 (24 residues), see Phobius details amino acids 228 to 246 (19 residues), see Phobius details amino acids 278 to 293 (16 residues), see Phobius details amino acids 378 to 402 (25 residues), see Phobius details PF28597: T2SSF_N" amino acids 2 to 41 (40 residues), 48.8 bits, see alignment 5e-17 TIGR02120: type II secretion system protein F" amino acids 4 to 408 (405 residues), 448.1 bits, see alignment E=1.8e-138 PF00482: T2SSF" amino acids 75 to 198 (124 residues), 113.2 bits, see alignment E=8.1e-37 amino acids 278 to 400 (123 residues), 94 bits, see alignment E=7.2e-31

Best Hits

Swiss-Prot: 42% identical to GSPF_PSEAE: Type II secretion system protein F (xcpS) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02455, general secretion pathway protein F (inferred from 71% identity to pol:Bpro_1331)

Predicted SEED Role

"General secretion pathway protein F / Type II secretory pathway, component PulF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (409 amino acids)

>GFF1392 General secretion pathway protein F / Type II secretory pathway, component PulF (Hydrogenophaga sp. GW460-11-11-14-LB1)
VPAYTFEALDAQGATQKGLIDADTARAARSMLRARALVPLLVEPAAGSPGASAAKGFNIT
LWGGRAFSATALAVWTRQLAGLVAAGLPLERALSALTEESEDEKQRNLMASLRSEVNGGS
TFARALAQHPREFSPIYTGVIAAGEQSGLLGTVLERLADDLEAREALKNKIVAASLYPAI
VTLVAIVIVVFLVSYVVPQVANVFAGSKRALPFLTVVMLGLSDFVRSYGWFMLALLALGV
GGVVFARRNEAIRLRMDAAWLRLPLVGRLARGYNAARFAATLAMLAAAGVPILRALQTAA
ETLSNQAMRADALDTVVLVREGAPLASALGSKKRFPPLVSMFARLGEQTGQLPSMLDRAA
KQLGDEVQRRAMHMATILEPLLIVGMGLVVMLIVLAVLMPIIQLNQLVS