Protein Info for PS417_07065 in Pseudomonas simiae WCS417

Annotation: tripartite tricarboxylate transporter TctA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 45 to 72 (28 residues), see Phobius details amino acids 109 to 134 (26 residues), see Phobius details amino acids 140 to 162 (23 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details amino acids 205 to 225 (21 residues), see Phobius details amino acids 249 to 278 (30 residues), see Phobius details amino acids 307 to 325 (19 residues), see Phobius details amino acids 331 to 350 (20 residues), see Phobius details amino acids 356 to 376 (21 residues), see Phobius details amino acids 385 to 407 (23 residues), see Phobius details amino acids 411 to 428 (18 residues), see Phobius details amino acids 435 to 452 (18 residues), see Phobius details amino acids 466 to 489 (24 residues), see Phobius details PF01970: TctA" amino acids 20 to 440 (421 residues), 491.5 bits, see alignment E=9.2e-152

Best Hits

KEGG orthology group: K07793, putative tricarboxylic transport membrane protein (inferred from 100% identity to pfs:PFLU1447)

Predicted SEED Role

"Tricarboxylate transport membrane protein TctA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UHL6 at UniProt or InterPro

Protein Sequence (504 amino acids)

>PS417_07065 tripartite tricarboxylate transporter TctA (Pseudomonas simiae WCS417)
MDTFGYLGQGFGVALSPYNLVTALCGTLIGTVVGLLPGLGPINGVALLIPIAFALGLPPE
SALILLAAVYLGCEYGGRISSILLNIPGEASTVMTTLDGYPMARKGLAGVALSLSAWSSF
IGAFIATCGMVLFAPLLAQWAIAFGPAEYFVLMVFAIVCLGGMAGDKPLKTFVAALIGLF
LSAVGIDANSGVYRFTGDNIHLTDGIQFVVLVLGLFSISEILLLLEKTHRGQEAVKATGR
MMFNLKEAGAVFVVNIRCGLLGFIMGVLPGAGATLASAVAYMTEKRLAGASGKFGQGDMR
GLAAPETAIGASACGALVPMLTLGVPGSGTTAVMIGALSLYNITPGPLLFQQQPDIVWGL
IASLFVANIMLVILNIPMIRIFTRILAVPNWALVPVIAIITAIGVYAVHATTFDLFLMVG
IGIFGYILRKLDFPLSPVLLGFILGGLMEQNLRRALSISNGDLQILWSSPITFGVWVLTA
LMLAFPLIRIYRKRALQRRAVADV