Protein Info for GFF139 in Sphingobium sp. HT1-2

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 529 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details amino acids 58 to 82 (25 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 157 to 183 (27 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 248 to 271 (24 residues), see Phobius details amino acids 283 to 304 (22 residues), see Phobius details amino acids 315 to 333 (19 residues), see Phobius details amino acids 431 to 455 (25 residues), see Phobius details amino acids 470 to 491 (22 residues), see Phobius details amino acids 499 to 519 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 22 to 242 (221 residues), 102.3 bits, see alignment E=3.1e-33 amino acids 433 to 528 (96 residues), 23.7 bits, see alignment E=2.2e-09 PF07690: MFS_1" amino acids 24 to 335 (312 residues), 94.5 bits, see alignment E=6.4e-31

Best Hits

KEGG orthology group: None (inferred from 87% identity to sch:Sphch_0758)

Predicted SEED Role

"putative sugar transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (529 amino acids)

>GFF139 Uncharacterized MFS-type transporter (Sphingobium sp. HT1-2)
MTQVVGGDYVMDAKRDRLVITASALGTVFEWYDFYIYGVLAPIIGRTFFPTDNPTVELLY
SLAGFAIGFGFRPLGAMLFGYLGDRLGRKYTFLATIVLMGLATAGVGLTPSAASIGVAAP
VILILLRIAQGLALGGEYGGAAIYVAEHAPAGKRGFYTSFIQGGVIGGFILSLIVVVGTQ
WIVGMEVWDAWGWRIPFIFSLALLAISLWMRLMLRESPVFTAMKKAGQQAKNPLKEAFTA
PGNRKRMLVAMIGIAAGFTVIAYTVMFQALYFLQSGLHVAPGIAQLLVGGSAFAGMASFI
FFGWLSDRVGRKKPIVIGYALVLLLVMPLYQYMGATANPALTQAAARAPVMVSGPDCRFD
PFAKIQPTACGKLLDHFSKSGIPYEKRSGLAPAVSIGGVAVADLSNDGIDAALTAQGYDF
GVVRPDWPRALMLFAALLLLWTLSGATYGPVAALLSEYFPARIRYSSLSIPYHIGTGYFG
GFLPLVSQYIVARTGDPYAGLWYTIAVVALALVTCLVALPETKGRPLDA