Protein Info for GFF1359 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Sodium-dependent phosphate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 46 to 71 (26 residues), see Phobius details amino acids 76 to 97 (22 residues), see Phobius details amino acids 104 to 121 (18 residues), see Phobius details amino acids 133 to 152 (20 residues), see Phobius details amino acids 171 to 196 (26 residues), see Phobius details amino acids 200 to 226 (27 residues), see Phobius details amino acids 238 to 257 (20 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details TIGR00704: Na/Pi-cotransporter II-related protein" amino acids 1 to 308 (308 residues), 440.8 bits, see alignment E=3.5e-136 PF02690: Na_Pi_cotrans" amino acids 13 to 147 (135 residues), 127.2 bits, see alignment E=4.8e-41 amino acids 159 to 241 (83 residues), 29.7 bits, see alignment E=6.1e-11 TIGR01013: sodium-dependent inorganic phosphate (Pi) transporter" amino acids 67 to 520 (454 residues), 537.1 bits, see alignment E=3.8e-165

Best Hits

Swiss-Prot: 100% identical to YJBB_SALTY: Uncharacterized protein YjbB (yjbB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03324, phosphate:Na+ symporter (inferred from 100% identity to sea:SeAg_B4441)

MetaCyc: 93% identical to putative inorganic phosphate export protein YjbB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-470

Predicted SEED Role

"Sodium-dependent phosphate transporter" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (543 amino acids)

>GFF1359 Sodium-dependent phosphate transporter (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
VLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKKPLAFCAGIGVTALVQS
SNATTLLVTSFVAQDLVALTPALVIVLGADVGTALMARILTFDLSWLSPLLIFIGVIFFL
GRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGVQVIFASLTGDIMLDALIGAM
FAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANLGSGLLAMLNNSAANAAARRVAL
GSLLFKLIGSLVILPFVHPLANLMDELSLPKSELVIYFHVFYNLVRCLAMVPFAELMARF
CKRIIRDEPELDTHLKPKHLDVSALDTPTLALANAAREVLRIGDAMEQMMEGLKKVMHGE
PREEKALRKLADDVNVLYTAIKLYLARMPKDELAAEESRRWAEIIEMALNLEQASDIIER
MGSEIADKSLAARRAFSEEGLKELDALYDQLLSNLQLAMSVFFSGDVTSARRLRRSKHRF
RILNRRYSHAHVDRLHQQNVQSIETSSLHLGLLGDMKRLNSLFCSVAYSVLEQPDQDEER
GEY