Protein Info for GFF1350 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cytochrome c-type biogenesis protein Ccs1/ResB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 717 transmembrane" amino acids 25 to 47 (23 residues), see Phobius details amino acids 68 to 73 (6 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 651 to 669 (19 residues), see Phobius details PF05140: ResB" amino acids 27 to 706 (680 residues), 448.1 bits, see alignment E=2.2e-138

Best Hits

KEGG orthology group: K07399, cytochrome c biogenesis protein (inferred from 69% identity to aaa:Acav_0958)

Predicted SEED Role

"Cytochrome c-type biogenesis protein Ccs1/ResB" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (717 amino acids)

>GFF1350 Cytochrome c-type biogenesis protein Ccs1/ResB (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTVSTQGLHIRTGSRIVSELVELLSSMRFAISLLTVICIASVIGTVVKQHEPFINYVNQF
GPFWADVFASAHLYSVYSAWWFLLILAFLVISTSLCIARNTPKILADFKAYKENIREQSL
KAFPHRAEGELGETPEAAANRIGQTLLGSGWKVKLQSRTTAAGTGWMVAAKAGAANKIGY
LAAHSAIVLVCIGGLLDGDLMVRAQTWFNGKTPFMGGGLIADVPAQHRLSASNPTFRGNL
LVTEGTTAGTAILAQPQGVLLQDLPFSVELKKFIVEYYDTGMPKLFASEIVIHDNETGES
KDARVEVNHPASHRGINIYQSSFDDGGSRVKLQAVPLNGPTRPFEIEGTIGSSTALSNGD
DKLTLEYTGLRVINVENFASSNAADGVDVRKVDLRGSIESRLGSGHKTVTEKTLRNVGPS
VSYKLRDAAGQAVEYHNYMLPVEIDGARVYLLGLRETPAEPFRYLRIPVDDKDGLDGFVR
LRAALSDAQMRDLAVRRYAASAVEDGRPELAEALAASAARALGLFAGAESVSAPGVQPVA
NGAGEKPIRGGLQAVSAFLENNVPAAERERASDVLVRILNGTLFELMQISRERAGLPPLE
RSEASQQFMSQAVISLSDTFFYPAPMTFQLKDFTHVQASVFQVARAPGQNIVYLGCLLLI
LGVFAMLYVRERRLWVWLSPSGEQASQARMALSSNRKTMDADREFEMLKTQLLKVQP