Protein Info for GFF1345 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 transmembrane" amino acids 12 to 39 (28 residues), see Phobius details amino acids 41 to 61 (21 residues), see Phobius details amino acids 67 to 90 (24 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 189 to 216 (28 residues), see Phobius details amino acids 227 to 256 (30 residues), see Phobius details amino acids 263 to 286 (24 residues), see Phobius details PF02653: BPD_transp_2" amino acids 16 to 280 (265 residues), 132.1 bits, see alignment E=1.1e-42

Best Hits

KEGG orthology group: K01997, branched-chain amino acid transport system permease protein (inferred from 81% identity to reh:H16_A3659)

Predicted SEED Role

"High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (292 amino acids)

>GFF1345 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MDFFGIPLSALMGQLLLGLVNGSFYAILSLGLAVIFGLLNVINFAHGALFMLGAVLTWMG
LNYLELNFWVMIVLAPLLVGLLGVVIERLFLRWIYRLDHLYGLLLTLGLTLMLEGVLRSA
YGVSGLPYSAPISGATNLGFMVMPNYRGFVVLASLVVCFATWYVIEKTKLGAYLRAGTEN
PRLVEAFGINVPLMVTLTYGFGVALAGLAGVLAAPIMQVSPLMGQNLIIIVFAVVVIGGM
GSILGTILTGLGLGIVEGLTKVFYPEASSTVVFVIMAIVLLIRPAGLFGKEK