Protein Info for GFF133 in Xanthobacter sp. DMC5

Annotation: Anhydromuropeptide permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 32 to 55 (24 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 103 to 121 (19 residues), see Phobius details amino acids 127 to 149 (23 residues), see Phobius details amino acids 172 to 192 (21 residues), see Phobius details amino acids 204 to 225 (22 residues), see Phobius details amino acids 261 to 286 (26 residues), see Phobius details amino acids 298 to 318 (21 residues), see Phobius details amino acids 325 to 347 (23 residues), see Phobius details amino acids 353 to 378 (26 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details amino acids 417 to 438 (22 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 401 (367 residues), 52.5 bits, see alignment E=3.7e-18 PF13000: Acatn" amino acids 37 to 217 (181 residues), 44.9 bits, see alignment E=6.5e-16

Best Hits

KEGG orthology group: K08218, MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG (inferred from 88% identity to xau:Xaut_1449)

Predicted SEED Role

"AmpG permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>GFF133 Anhydromuropeptide permease (Xanthobacter sp. DMC5)
MTEQSLSPTGADAPRRRSLKEAVALYTQRDVLSVSLLGFSSGLPLALTGGTLSLWMKDVG
VTLTAIGLFSLVGLPYTLKFLWAPVLDAVDVPILSRLLGRRRGWLLACQIVLIAAIAALA
LQDPISAPFGVAACALAVAIASATQDIAVDAFRVERLESASEQAAGMAGYVTGYRIAMLA
TGAGVIALVAYLETALGLPRGTSWFWGYMIAAGCVAIGVIATLFAREPRAPVRAPDEGTG
HRLVATTVGAFGEFLRRNQAVMILLFVMLFKFCDAFAGVLTGPFVLDIGFSKATYVEIVK
VVGFGGTIAGSFVGAWIARARPLVTCLWISGVLQITSNLGFTLQAYVGPNEAVLTGVILI
ENFTSAIGTVIFVAYLSALCGAREHTATQYALLTALTAVGRTLLGSSSGAIAEASGWPLF
FILTAVAGLPGLAALGWLQMKGHFAELARDRA