Protein Info for PS417_00665 in Pseudomonas simiae WCS417

Annotation: RND transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 10 to 469 (460 residues), 374 bits, see alignment E=5.4e-116 PF02321: OEP" amino acids 65 to 257 (193 residues), 83.8 bits, see alignment E=7.2e-28 amino acids 287 to 467 (181 residues), 88.6 bits, see alignment E=2.3e-29

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU0131)

Predicted SEED Role

"Outer membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U8B9 at UniProt or InterPro

Protein Sequence (481 amino acids)

>PS417_00665 RND transporter (Pseudomonas simiae WCS417)
MKRVAWLTLSLISLSACTVGPDFQRPQGPQVTQWSEPQGRQAASRAVNDPLQERWWDVFH
DEQLSALTRRALTDNLDLKLASSRLQQSRAVRQVTTAERYPNVNANGDYQRKRNSGKGLS
DPSGNNGRSAFNQWDMGFSASWELDFWGRVKRETEAADATLQVAENDRRAVLLSVLAETA
QNYIQLRGVQNTRAVTEQNLDVARHSLKLSQLRLADGVATDLDVAEAAAQVAAIEARLPD
LQQRQDQLINALSLLMGEPPQALHAQLSKDAAVPQTQRQVAIGLPSELAERRPDIRQAEA
RLHAATASIGVAKGDFYPRITLSGSLGSQAMQLSDFGSWGSRAFAFGPQFSLPLFNGGRL
QGMLNLREAQQQEAALAYQQTVLRAWHEIDDQLTRYNASQLRRDSLAEAVRQNQIALRTA
QQQYVEGVVDFVNVLTVQSALLATQEQWVDSSTGVSLAMVGLYKALGGGWESVYPLQTVG
R