Protein Info for GFF1304 in Variovorax sp. SCN45

Annotation: Glutamate/aspartate ABC transporter, permease protein GltJ (TC 3.A.1.3.4)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 83 to 107 (25 residues), see Phobius details amino acids 125 to 146 (22 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 301 to 322 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 76 to 144 (69 residues), 47.4 bits, see alignment E=1.1e-16 PF00528: BPD_transp_1" amino acids 98 to 327 (230 residues), 63.5 bits, see alignment E=1.2e-21

Best Hits

KEGG orthology group: K09970, general L-amino acid transport system permease protein (inferred from 95% identity to vpe:Varpa_3218)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>GFF1304 Glutamate/aspartate ABC transporter, permease protein GltJ (TC 3.A.1.3.4) (Variovorax sp. SCN45)
MRRDAVASSRRGVWLAWAVQVLLVLAVVAGAVWVVHHALEVLRARGVRSGFDFLTEPAGF
SISEGWLDFDASQPFWRAFLAGLINTVRAAVPAAIFSVVLGTLIGIGRLAPHVLLRGICT
AYVELLRNVPLLVQLLMLAFAMANLLPDPTEPVHLLPGVWLSKGGLSVPWPVAAEGGWWP
THFEWPERGNFGVSGGAALSPEYVTIVAGLTFYSAAFVAEIVRAGILSVSQGQVLAGQAL
GLSSGQQLRIVILPQALRVIVPSLTNQLLSLTKNSSLAVAVGYPELVSVANTTIGSNGRA
FECIAIIMAVYLLLSLLISFGMNRYNARVALRGWR