Protein Info for PS417_00655 in Pseudomonas simiae WCS417

Annotation: DSBA oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 transmembrane" amino acids 23 to 47 (25 residues), see Phobius details amino acids 67 to 87 (21 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 121 to 145 (25 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 248 to 266 (19 residues), see Phobius details amino acids 286 to 310 (25 residues), see Phobius details amino acids 324 to 346 (23 residues), see Phobius details amino acids 353 to 372 (20 residues), see Phobius details amino acids 384 to 402 (19 residues), see Phobius details amino acids 414 to 434 (21 residues), see Phobius details amino acids 482 to 500 (19 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 430 (396 residues), 87.7 bits, see alignment E=3.7e-29

Best Hits

KEGG orthology group: None (inferred from 97% identity to pfs:PFLU0129)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0L2 at UniProt or InterPro

Protein Sequence (511 amino acids)

>PS417_00655 DSBA oxidoreductase (Pseudomonas simiae WCS417)
MTSLAAPTLAAAAKPTAMTPPVFGPRIIIGLVGVLLAVLVSGLNEMVTKVALADIRGALY
IGFDEGTWLVAAYTATSVAAMAFAPWCSVTFSLRRFTLCAIGLFTALGILCPFAPNYESL
LVLRTVQGLAGGALPPMLMTVALRFLPANVKLYGLAGYALTATFGPSLGTPLAALWTEYV
GWQWAFWQIVAPCLLAMIAVAYGLPQDPIRLERFKQFNWRGLLLGFPAICMLVIGILQGN
RLDWFESGLITFLLGGGGVLLVLFMVNEWSQPIPFFKLQMLGLRNLSFALIVLAGVLMVL
TSVIIIPSSFLAQVQGYRPLQTAPVMLLMAIPQLIALPLVAALCNLRWVDCRWVLGIGLG
MLVLCCVGSAHLTSEWIRDDFYGLYLLQIFGQPMAVLPLLMLSTGSIQPMDGPFASAWFN
TIKGLAAVIATGVLDTLTTQRLHFHSTMLVDRLGNSPLADGDAPGLAHRLHEQAVVLTSS
DLYYVMAAVAVALILLIFWMPTRIFPPRAPT