Protein Info for GFF1285 in Variovorax sp. SCN45

Annotation: Alkyl hydroperoxide reductase subunit C-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 PF08534: Redoxin" amino acids 7 to 143 (137 residues), 55 bits, see alignment E=1.2e-18 PF00578: AhpC-TSA" amino acids 7 to 135 (129 residues), 105.2 bits, see alignment E=3.4e-34 PF10417: 1-cysPrx_C" amino acids 157 to 183 (27 residues), 37.5 bits, see alignment (E = 2.7e-13)

Best Hits

Swiss-Prot: 61% identical to PRDXL_DICDI: 1-Cys peroxiredoxin (DDB_G0282517) from Dictyostelium discoideum

KEGG orthology group: None (inferred from 97% identity to vap:Vapar_2963)

Predicted SEED Role

"Alkyl hydroperoxide reductase subunit C-like protein" in subsystem Oxidative stress or Rubrerythrin or Thioredoxin-disulfide reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (213 amino acids)

>GFF1285 Alkyl hydroperoxide reductase subunit C-like protein (Variovorax sp. SCN45)
MATLRLGDTAPNFTQDSSEGPIDFYQWAGDSWVVFFSHPADFTPVCTTELGKTAALSGEF
AKRGVKPIALSVDPATKHKEWIGDINETQNTTVNFPIIADADRKVADLYDLIHPNASTTA
TVRSVYIIDPKKIIRTTITYPASTGRNFDEILRVIDSLQLTDSHKVATPVNWKDGDDVVI
VPSIQDPAELAERFPKGFKAVKPYLRITPQPNK