Protein Info for GFF1277 in Variovorax sp. SCN45

Annotation: Alkanesulfonates-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF04069: OpuAC" amino acids 36 to 244 (209 residues), 41.1 bits, see alignment E=2.5e-14 TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 37 to 318 (282 residues), 188.5 bits, see alignment E=7.8e-60 PF09084: NMT1" amino acids 63 to 256 (194 residues), 46.1 bits, see alignment E=9e-16 PF12974: Phosphonate-bd" amino acids 76 to 196 (121 residues), 30.4 bits, see alignment E=4e-11

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 57% identity to hse:Hsero_4588)

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (323 amino acids)

>GFF1277 Alkanesulfonates-binding protein (Variovorax sp. SCN45)
MHHIPSLSRRRLLQAGGAAAIAATAAPLFAQTRTQTLRIGYQKFNTLNILKGTGQLEKAL
APAGVKVEWSEFLGGSQLSEALAAGAIDFGHASDGIGVFQQASGKGLAYLAAESPYPGGV
GFLVPRDSPIRGVRDLKGKKVVTGRGYNTQYVLIRALEAAGLRYEDIEPVYILTASDTIA
AYQSGSVAAIGLWDPFLAAAQLATDSRLLFDGAGLSGNRTYHFAQPGFARANQEVLRTVF
AELRKANEWAQAHPAEVVATLAPQLKVEPKVLALATERRQYGVVALTPAIAREQQGLADV
FAQLKLIPKPIEVKDAFLDLNLV