Protein Info for GFF127 in Xanthobacter sp. DMC5

Annotation: Cyclopropane-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 PF02353: CMAS" amino acids 121 to 385 (265 residues), 296 bits, see alignment E=9.4e-92 PF13489: Methyltransf_23" amino acids 172 to 288 (117 residues), 39.5 bits, see alignment E=1.8e-13 PF13847: Methyltransf_31" amino acids 178 to 284 (107 residues), 40.1 bits, see alignment E=1e-13 PF05175: MTS" amino acids 180 to 281 (102 residues), 28.3 bits, see alignment E=4.4e-10 PF13649: Methyltransf_25" amino acids 183 to 277 (95 residues), 58.9 bits, see alignment E=2.4e-19 PF08242: Methyltransf_12" amino acids 184 to 278 (95 residues), 39.8 bits, see alignment E=2.3e-13 PF08241: Methyltransf_11" amino acids 184 to 280 (97 residues), 46.6 bits, see alignment E=1.5e-15

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 79% identity to xau:Xaut_3122)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>GFF127 Cyclopropane-fatty-acyl-phospholipid synthase (Xanthobacter sp. DMC5)
MERLLEILLRRVIVDGALKVTTASGRSFTVSTPPRAGPPPAPLAVRFTSAEAERGIILDP
ELKLGEAYMDGTLVMEVGSIADLLALLMSQPAAFNPSVPAKAFHVLRRLGRRIAQFNPPE
RSRRNVAHHYDIDGRLYSLFLDHDRQYSCAYFEHEGQSLDDAQLAKKRHIAAKLVLDRPG
LKVLDIGSGWGGLALYLAEMAGAQVSGVTLSQEQLALATARADERGMAGHVSFALRDYRD
VEGPFDRVVSVGMFEHVGVAHYAEFFRKAKSLLKEDGVMLLHAIGRSDPPGVTNPFIARY
IFPGGYIPALSEVTPHIEKSGLVVTDIELLRLHYAETLKAWRQRFLARREEAARLTDERF
CRMWEFYLAASEMGFWHQGLNVFQIQLARRQDAVPLTRGYIAEAEARLRRAEAGCATPLR
LAGE