Protein Info for GFF127 in Sphingobium sp. HT1-2

Annotation: Transcriptional regulator, Xre family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 PF13560: HTH_31" amino acids 10 to 60 (51 residues), 32.1 bits, see alignment 2.3e-11 PF01381: HTH_3" amino acids 13 to 63 (51 residues), 33.3 bits, see alignment 8.4e-12 PF06114: Peptidase_M78" amino acids 189 to 311 (123 residues), 77.4 bits, see alignment E=1.8e-25 PF09856: ScfRs" amino acids 312 to 468 (157 residues), 222.2 bits, see alignment E=6.2e-70

Best Hits

KEGG orthology group: K07110, (no description) (inferred from 93% identity to sch:Sphch_0765)

Predicted SEED Role

"Transcriptional regulator, XRE family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (471 amino acids)

>GFF127 Transcriptional regulator, Xre family (Sphingobium sp. HT1-2)
MARGNRIFAGPRLRQLRLDHRMDQATMAQALGISVSYLSQMENDDRPLTAKVKAALANAF
PTDWASFDSREDEQLLGAFAFALSHPELPGPALEPERIEKLHLQFPEFAARYVDLYNAHM
RANERINMIEEAIANDHEVQARLPWEAARDWFHEAGNYVHSLDCLAEEMAESFAQGQVLD
EGMLVEALARRHGIETLIAETPDSALRAYRAADRQLFINAALPTESRKFMLAHQLMMLEG
QAVIADVVRKAGLPVTGADRLLAIGLGNYAAGALLMPYAPFREAARTMRHDIDRLARTFG
VSFEQACHRLSTLQRPGLRGIPFFFCRVDMAGNITKRHSATRLQFARFGGACPLWNVHEA
VAVPDRINVQLGETPDGVRYVSMAKGLVKPSGSYKRTPRRFAVVLGCEVAHAANFVYADG
LHLQEEGAATPIGITCRLCSRQSCDQRAFPPADRPIHVDPDNRQIVPYWIG