Protein Info for GFF1269 in Xanthobacter sp. DMC5

Annotation: Glutathione-regulated potassium-efflux system protein KefC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 49 (18 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 87 to 109 (23 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 187 to 208 (22 residues), see Phobius details amino acids 228 to 254 (27 residues), see Phobius details amino acids 273 to 294 (22 residues), see Phobius details amino acids 301 to 320 (20 residues), see Phobius details amino acids 332 to 353 (22 residues), see Phobius details amino acids 364 to 386 (23 residues), see Phobius details TIGR00932: transporter, monovalent cation:proton antiporter-2 (CPA2) family" amino acids 17 to 290 (274 residues), 249.7 bits, see alignment E=2e-78 PF00999: Na_H_Exchanger" amino acids 19 to 380 (362 residues), 215.3 bits, see alignment E=1.3e-67 PF02254: TrkA_N" amino acids 409 to 519 (111 residues), 69.1 bits, see alignment E=4.2e-23

Best Hits

KEGG orthology group: K11747, glutathione-regulated potassium-efflux system protein KefB (inferred from 85% identity to xau:Xaut_4650)

Predicted SEED Role

"putative Glutathione-regulated potassium-efflux system protein KefB" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (613 amino acids)

>GFF1269 Glutathione-regulated potassium-efflux system protein KefC (Xanthobacter sp. DMC5)
MPVDEHALFAGALAFMCAAVIAVLVAKRIGFSPIVGYLLVGIAIGPIGFNVADPSVVHTV
AELGVVMLLFLVGLELKPSHLLSMGHYIFGLGTAQLVLTSLAFALLAYFGLGFGVAAAVV
SGLALSVSGTAIALQLVGERGDLASPYGQRTFSILLFQDIAVVPLLALVPLLAPGGESEI
HDPKGTLIQAGMAVGAIAVIVVAGRYLLNPLFRVLARSGAREAMTAAALMVVLGAAGLME
IAGMSAAMGAFLAGLLLSESTFRHELEANVDAFRGLLLAIFFMSIGMTLNIDVILHHIPR
LVVGALAVAVIKSVVVYLVFRADNIAPGDSLRASVALMAAGEFAFVLFPLGLANGILRTE
QTDLLIALAALTMVLGPLLFAGVSRYLPRFTPPAPEPPADDFTDADGSVLVIGFGRFGQI
VSQCLLAQDVSVTIIDKDVEMIQSAGRFGVHIYYGDGTRLDVLRAAGAETMEVICICVDN
KEDANRIVEIVRTSIQGPRLFVRSFDRVHSMELVRLGVDFELRETLESALSFGARTLEAL
GVSESAAEARIADVRERDRARLERQMQDGLFAGGDAFSRPKVEPEPLTEPERRARPLNPE
AQDILTHETEFSG