Protein Info for GFF1265 in Variovorax sp. SCN45

Annotation: cAMP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 transmembrane" amino acids 273 to 293 (21 residues), see Phobius details PF19307: SrpI-like" amino acids 60 to 300 (241 residues), 334.5 bits, see alignment E=1.6e-104

Best Hits

Swiss-Prot: 73% identical to SRPI_SYNE7: Protein SrpI (srpI) from Synechococcus elongatus (strain PCC 7942)

KEGG orthology group: None (inferred from 99% identity to vap:Vapar_1893)

Predicted SEED Role

"Major membrane protein I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (310 amino acids)

>GFF1265 cAMP-binding protein (Variovorax sp. SCN45)
MSATVGGTTALGDNAARQLANATKTVPQLETISPRWLTHLLQWVPVEAGIYRVNKVKNPE
SIKVTCTSREEENQLPRTFVDYEENPREHYLNAVSTVLDVHTRISDLYSSPHDQIKEQLR
LTIETIKENQESELINNPDYGLLAQVTEEQRIFPLTGAPTPDDLDELLTKVWKEPAFFLT
HPLAIAAFGREATRRGTPPPTVSLFGSQFITWRGIPLIPSNKVPVADGKSKILLLRVGDK
RQGVVGLFQPGLSGEQGPGLSVRFMGINNHAIASYLISLYCSLAVLTTDALAVLDDVEIG
KYHDYPDTYK