Protein Info for GFF1243 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868
Annotation: COG3267: Type II secretory pathway, component ExeA (predicted ATPase)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 99% identity to sec:SCV51)Predicted SEED Role
"COG3267: Type II secretory pathway, component ExeA (predicted ATPase)"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (322 amino acids)
>GFF1243 COG3267: Type II secretory pathway, component ExeA (predicted ATPase) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868) MRVEVMEHYGLTQSIEQAGYYETAHHKQLMKDIKGAIREGRLIAVCGVVGSGKTVTLRRL QQQLLDENKIIVARSLSVDKQSVRLATLINALFYDLAQDKQVQIHKQGERRERELQELVK KGKRPVALFVDEAHDLNGNTLTGLKRLMEVVEDGGGRLSVVLAGHPKLRNDLRRPTMEEI GYRTDIFTLDGITGSQREYIQWLLKTSTGKGKPEDILTTEAVDLLAMKLRTPLQVQLHLT LAMEAGYQTGEKPITATLVESVLSRQLDDLEPTLTRHGYRLKDMVEQFDAKPAEIRALFN NQLDPARTAELRDRMLAVGLPI