Protein Info for GFF1240 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Virulence genes transcriptional activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details PF00126: HTH_1" amino acids 8 to 65 (58 residues), 50.2 bits, see alignment E=9.8e-18

Best Hits

Swiss-Prot: 100% identical to VRPR_SALTY: Virulence genes transcriptional activator (mkaC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 99% identity to sec:SCV02)

Predicted SEED Role

"Virulence genes transcriptional activator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (297 amino acids)

>GFF1240 Virulence genes transcriptional activator (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MDFLINKKLKIFITLMETGSFSIATSVLYITRTPLSRVISDLERELKQRLFIRKNGTLIP
TEFAQTIYRKVKSHYIFLHALEQEIGPTGKTKQLEIIFDEIYPGSLKNLIISALTISGQK
TNIMGRAVNSQIIEELCQTNNCIVISARNYFHRESLVCRTSVEGGVMLFIPKKFFLCGKP
DINRLAGTPVLFHEGAKNFNLDTIYHFFEQTLGITNPAFSFDNVDLFSSLYRLQQGLAML
LIPVRVCRALGLSTDHALHIKGVALCTSLYYPTKKRETPDYRKAIKLIQQELKQSTF