Protein Info for GFF1238 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 33 to 52 (20 residues), see Phobius details amino acids 64 to 82 (19 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 119 to 142 (24 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 181 to 206 (26 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 250 to 268 (19 residues), see Phobius details amino acids 274 to 292 (19 residues), see Phobius details PF00892: EamA" amino acids 5 to 136 (132 residues), 44.3 bits, see alignment E=1.1e-15 amino acids 156 to 289 (134 residues), 38.5 bits, see alignment E=7e-14

Best Hits

KEGG orthology group: None (inferred from 83% identity to aav:Aave_3629)

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (293 amino acids)

>GFF1238 Integral membrane protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSLNAFCLIVLAGLIHAGWNIVAKKAAGDARFAFFNAFLMMLVWAPLGWWLGREEVPRWG
ATEWGFVVASGVLHVFYYVILLRGYRKADLTVVYPMARGSGPLLSSLVAIVFLGERISAL
GAVGIAGVVGGVFLIAGGPGLLRAAHDPVARRRVHKGMVYGVLTGVFIAAYTVVDGYAVK
VLLMSPILIDYMGNFVRLGLLAPAVLRDIPTARQLWRVQWRYALLVAVVSPIAYVLVLYA
MREAPLSHVAPAREVSMLFAALIGGHLLGEGDRAARILGALCIAAGVTALALG