Protein Info for GFF1200 in Sphingobium sp. HT1-2

Annotation: Putative glycosyl hydrolase of unknown function (DUF1680)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 802 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF07944: Beta-AFase-like_GH127_cat" amino acids 54 to 440 (387 residues), 408.4 bits, see alignment E=4.6e-126 PF20736: Glyco_hydro127M" amino acids 454 to 548 (95 residues), 90.5 bits, see alignment E=9.1e-30 PF20620: DUF6805" amino acids 661 to 779 (119 residues), 66.3 bits, see alignment E=5.5e-22

Best Hits

KEGG orthology group: K09955, hypothetical protein (inferred from 59% identity to aex:Astex_1338)

Predicted SEED Role

"Putative glycosyl hydrolase of unknown function (DUF1680)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (802 amino acids)

>GFF1200 Putative glycosyl hydrolase of unknown function (DUF1680) (Sphingobium sp. HT1-2)
MSHRHTPLSRRAMLLAATAAATAPAWQGWSSVAHAATGSALPESARALPLQATRLLPSPF
ADAVEGNRRYLLRLEPDRLLHNFRKHAGLTPKGAIYGGWENDTIAGHTLGHYLTALALMH
AQTGDTECARRAAYIIDELAACQAAAGDGYVAGFTRRRDDVIEDGRLIFPEIMRGDIRSA
GFDLNGCWVPFYNWHKLFAGLFDAETHLGNSQARGVALALAAYIDGVFVKLDDAQVQQVL
DCEHGGINESFAELHARTGDPRWLALATRLRHRKVLDPLAQRQNSLPWIHANTQIPKLIG
LARLHEITGNAADAIATNFFWETVVGQYSYVIGGNADREYFPDPGTISKHITEQTCESCN
SYNMLKLTRHLYAWKPEARLFDYYERAHINHILAHQNPATGMFAYMVPLMSGSHRVWSEP
FDDFWCCVGSGMESHAKHGESIWWEDADRPADMLIANLYIPSEADWAARGAKLRIETGYP
FDGHIALSIPKLARAGRFTLALRIPGWCQGARIAVNGAPLPAPRITDGYALIDRKWKAGD
QVTLDLPMALRIEATPDDPRTIALLHGPVVLAADLGAADQPFDGPAPALVAADVTQGFAA
TTAAVPAYRTAGIGKPADLSFAPFFQQRDRRTAVYFKRFTQQEWGVEQQAFAVEQARLRD
LERRSVDVMHLGEMQPERDHGLEAKLSYTTTYRGRHGRDARTDGHFQFRMKVKPGPLILQ
ATYWGEERNRLFDILVDGQKIATQKLDADRPGEFFDVTYAIPEALTRGKSTVMIRVQPAP
GMTRAGPMFGARIFTPAGETRT