Protein Info for PS417_05970 in Pseudomonas simiae WCS417

Annotation: chemotaxis protein CheR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 PF01739: CheR" amino acids 68 to 241 (174 residues), 133.6 bits, see alignment E=6.2e-43

Best Hits

KEGG orthology group: K13486, chemotaxis protein methyltransferase WspC (inferred from 90% identity to pfs:PFLU1221)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TWP6 at UniProt or InterPro

Protein Sequence (419 amino acids)

>PS417_05970 chemotaxis protein CheR (Pseudomonas simiae WCS417)
MSSDPRFFAFLKERIGLDVASVGEAIIQRAVRQRSQAVNAQTAGEYWQHLQSSEDEQQAL
IEAVIVPETWFFRYPESFATLARLAKARLAEIKQMRALRILSLPCSTGEEPYSIAMALLD
AGLAPHQFKVLGLDVSPLSVERARRGVYGRNSFRGGDIAFRDRHFTEYDDGYHIAERVRE
QVRLQVGNLLDPGLLANEASYDFVFCRNLLIYFDQPTQKQVFDVLKGLTHVDGVLFIGPA
EGSLLGRHGMRSIGVPQSFAFSRHAEPVKPEPVFVPIAAPIPPRSAAPIPTKPRPFSTAR
AQVVPIKAPHTDAGDLLGRIATLANEGKSAEARAACEQYLSNHPPAAQVFYWLGLLSDVA
GSALEAQGYYRKALYLEPQHPQALMHLAALLESQGDSAGARRLQARAARSERADSESKR